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Diabetes mellitus and chronic kidney disease in the Eastern Mediterranean Region: findings from the Global Burden of Disease 2015 study
Version 4 2024-10-20, 00:00
Version 3 2024-06-19, 08:13
Version 2 2024-06-06, 00:48
Version 1 2022-01-20, 08:10
journal contribution
posted on 2024-10-20, 00:00 authored by Maziar Moradi-Lakeh, Charbel El Bcheraoui, Ibrahim Khalil, Raghid Charara, Ashkan Afshin, Haidong Wang, Michael Collison, Kristopher J Krohn, Adrienne Chew, Farah Daoud, Christopher D Blosser, Leslie Cornaby, Kyle J Foreman, Nicholas J Kassebaum, Laura Kemmer, Michael Kutz, Patrick Liu, Ben Zipkin, Johan Ärnlöv, Kalkidan Hassen Abate, Alireza Ahmadi, Hamid Ahmadieh, Muktar Beshir Ahmed, Ziyad Al-Aly, Khurshid Alam, Deena Alasfoor, Raghib Ali, Reza Alizadeh-Navaei, Juma M Alkaabi, Alaa Alkerwi, Rajaa Al-Raddadi, Khalid A Altirkawi, Nelson Alvis-Guzman, Erfan Amini, Nahla Anber, Palwasha Anwari, Solomon Weldegebreal Asgedom, Tesfay Mehari Atey, Leticia Avila-Burgos, Ashish Awasthi, Peter Azzopardi, Till Bärnighausen, Umar Bacha, Aleksandra Barac, Shahrzad Bazargan-Hejazi, Neeraj Bedi, Derbew Fikadu Berhe, Addisu Shunu Beyene, Zulfiqar A Bhutta, Boris Bikbov, Mulugeta M Birhanu, Zahid A Butt, Lucero Cahuana-Hurtado, David O Carpenter, Juan Jesus Carrero, Jee Young Jasmine J Choi, Hadi Danawi, Samath D Dharmaratne, Eric L Ding, Shirin Djalalinia, Kerrie E Doyle, Hedyeh Ebrahimi, Aman Yesuf Endries, Alireza Esteghamati, Maryam S Farvid, Seyed Mohammad Fereshtehnejad, Tesfaye FeyissaTesfaye Feyissa, Florian Fischer, Tsegaye Tewelde Gebrehiwot, Philimon N Gona, Sameer Vali Gopalani, Masako Horino, Mohamed Hsairi, Mihajlo B Jonas, Aida Jimenez-Corona, Denny John, Jost B Jonas, Amir Kasaeian, Andre Pascal Kengne, Ezra Belay Khan, Daniel Kim, Yun Jin Kim, Yohannes Kinfu, Katarzyna A Kissimova-Skarbek, Ai Koyanagi, Heidi J Larson, Anders Larsson, Yongmei Li, Paulo A Lotufo, Raimundas Lunevicius, Azeem Majeed, Reza Malekzadeh, Deborah Carvalho Malta, Mohsen Mazidi, Ziad A Memish, Walter Mendoza, Mubarek Abera Mengistie, George A Mensah, Haftay Berhane Mezgebe, Ted R Miller, Muktar Sano Kedir Mohammed, Shafiu Mohammed, Ulrich O Mueller, Gabriele Nagel, Cuong Tat Nguyen, Quyen Le Nguyen, Vuong Minh Nong, Jean Jacques N Noubiap, Felix Akpojene Ogbo, Alberto Ortiz, Erika Ota, Tejas Patel, Jonathan Pearson-Stuttard, Norberto Perico, Max Petzold, Farhad Pishgar, Farshad Pourmalek, Mostafa Qorbani, Vafa Rahimi-Movaghar, Rajesh Kumar Rai, Saleem M Rana, David Laith Rawaf, Salman Rawaf, Giuseppe Remuzzi, Andre MNN Renzaho, Satar Rezaei, Gholamreza Roshandel, Dietrich Rothenbacher, Mahdi Safdarian, Sare Safi, Saeid Safiri, Mohammad Ali Sahraian, Payman Salamati, Abdallah M Samy, Juan Ramon Sanabria, Maria Dolores Sanchez-Niño, Milena M Santric Milicevic, Benn Sartorius, Sadaf G Sepanlou, Masood Ali Shaikh, Diego Augusto Santos Silva, Dayane Gabriele Alves Silveira, Badr HA Sobaih, Rizwan Suliankatchi Abdulkader, Rafael Tabarés-Seisdedos, Arash Tehrani-Banihashemi, Mohamad Hani Temsah, Roman Topor-Madry, Bach Xuan Tran, Kingsley Nnanna Ukwaja, Olalekan A Uthman, Job FM van Boven, Tola UshulaTola Ushula, Andrea Werdecker, Abdulhalik Workicho, Mohsen Yaghoubi, Yuichiro Yano, Mehdi Yaseri, Naohiro Yonemoto, Mustafa Z Younis, Anthony Lin Zhang, Aisha O Jumaan, Theo Vos, Mohsen Naghavi, Simon I Hay, Christopher JL Murray, Ali H MokdadObjectives: We used findings from the Global Burden of Disease 2015 study to update our previous publication on the burden of diabetes and chronic kidney disease due to diabetes (CKD-DM) during 1990–2015. Methods: We extracted GBD 2015 estimates for prevalence, mortality, and disability-adjusted life years (DALYs) of diabetes (including burden of low vision due to diabetes, neuropathy, and amputations and CKD-DM for 22 countries of the EMR from the GBD visualization tools. Results: In 2015, 135,230 (95% UI 123,034–148,184) individuals died from diabetes and 16,470 (95% UI 13,977–18,961) from CKD-DM, 216 and 179% increases, respectively, compared to 1990. The total number of people with diabetes was 42.3 million (95% UI 38.6–46.4 million) in 2015. DALY rates of diabetes in 2015 were significantly higher than the expected rates based on Socio-demographic Index (SDI). Conclusions: Our study showed a large and increasing burden of diabetes in the region. There is an urgency in dealing with diabetes and its consequences, and these efforts should be at the forefront of health prevention and promotion.
