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Dietary Inflammatory Index and the Risk of Frailty Among Older Adults: A Systematic Review and Meta-Analysis
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posted on 2021-08-01, 00:00 authored by S Moradi, A Hadi, H Mohammadi, O Asbaghi, M Zobeiri, Wolf MarxWolf Marx, M H EntezariA systematic review and meta-analysis was conducted to comprehensively examine the association between Dietary Inflammatory Index (DII®) score and risk of frailty. Frailty risk were available from five studies comprising 13,908 older adults. Furthermore, frailty related parameters were extacted from two studies with 7,539 individuals. A pooled adjusted odds ratio analysis indicated that there was an association between DII® score and frailty risk (OR = 1.24, 95%CI: 1.6–1.33, P < 0.001, I2 = 0.0%). The results of frailty related parameters demonstrated that DII® score was associated with weakness risk (OR = 1.12, 95%CI: 1.05–1.19, P = 0.014, I2 = 0.0%), but not other frailty-related parameters including exhaustion, low BMI or low physical activity. The results of this meta-analysis suggest that older adults who exhibit higher DII® scores have an increased frailty risk. Further prospective cohort studies with longer follow-up periods, are needed to support this possible association between DII® score and frailty risk.
History
Journal
Research on AgingVolume
43Issue
7-8Article number
ARTN 0164027520948176Pagination
323 - 331Publisher
SAGE PUBLICATIONS INCLocation
United StatesPublisher DOI
ISSN
0164-0275eISSN
1552-7573Language
EnglishPublication classification
C1 Refereed article in a scholarly journalUsage metrics
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