File(s) under permanent embargo
Does the temperature of water ingested during exertional-heat stress influence gastrointestinal injury, symptoms, and systemic inflammatory profile?
journal contribution
posted on 2018-08-01, 00:00 authored by Rhiannon SnipeRhiannon Snipe, R J S CostaOBJECTIVES: The study aimed to determine the effects of temperature of ingested water during exertional-heat stress on gastrointestinal injury, symptoms and systemic inflammatory responses. DESIGN: Randomised cross-over study. METHODS: Twelve endurance runners completed 2h running at 60% v˙O2max in 35°C ambient temperature on three separate occasions, consuming 250±40mL water before and every 15min during running at either 0.4±0.4°C (COLD), 7.3±0.8°C (COOL), or 22.1±1.2°C (TEMP). Rectal temperature and gastrointestinal symptoms were recorded every 10min during exercise. Blood was collected pre, immediately and 1h post-exercise to determine plasma intestinal fatty-acid binding protein (I-FABP), cortisol, and inflammatory cytokine concentrations. RESULTS: Compared to TEMP, COLD and COOL blunted the rise in rectal temperature (2.0±0.5°C vs. 1.6±0.4°C and 1.7±0.4°C, respectively; trial×time, p=0.033). I-FABP increased post-exercise (419%, p<0.001), with a trend for reduced I-FABP on COLD and COOL (mean reduction 460pgmL-1 and 430pgmL-1, respectively), compared to TEMP (p=0.066). No differences were observed between trials for gastrointestinal symptoms, albeit a trend for increased upper-gastrointestinal symptoms on TEMP (p=0.087) compared to COLD and COOL was observed. IL-6, IL-1β, IL-8, IL-10 and IL-1ra increased post-exercise (p<0.05); however no differences were observed between trials. CONCLUSIONS: COLD and COOL water ingestion during exertional-heat stress ameliorates thermoregulatory strain compared to TEMP. However, this appears to have no effect on cytokine profile and minimal effect on intestinal epithelial injury and gastrointestinal symptoms.
History
Journal
Journal of science and medicine in sportVolume
21Issue
8Pagination
771 - 776Publisher
ElsevierLocation
Amsterdam, The NetherlandsPublisher DOI
ISSN
1440-2440eISSN
1878-1861Language
engPublication classification
C Journal article; C1.1 Refereed article in a scholarly journalCopyright notice
2018, Sports Medicine AustraliaUsage metrics
Categories
No categories selectedKeywords
Licence
Exports
RefWorks
BibTeX
Ref. manager
Endnote
DataCite
NLM
DC