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Dynamic and responsive growth factor delivery from electrospun and hydrogel tissue engineering materials

journal contribution
posted on 10.01.2018, 00:00 authored by Kiara F Bruggeman, Richard WilliamsRichard Williams, David R Nisbet
Tissue engineering scaffolds are designed to mimic physical, chemical, and biological features of the extracellular matrix, thereby providing a constant support that is crucial to improved regenerative medicine outcomes. Beyond mechanical and structural support, the next generation of these materials must also consider the more dynamic presentation and delivery of drugs or growth factors to guide new and regenerating tissue development. These two aspects are explored expansively separately, but they must interact synergistically to achieve optimal regeneration. This review explores common tissue engineering materials types, electrospun polymers and hydrogels, and strategies used for incorporating drug delivery systems into these scaffolds.

History

Journal

Advanced healthcare materials

Volume

7

Issue

1

Article number

1700836

Pagination

1 - 14

Publisher

Wiley

Location

London, Eng.

eISSN

2192-2659

Language

eng

Publication classification

C1 Refereed article in a scholarly journal