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Dynamic and responsive growth factor delivery from electrospun and hydrogel tissue engineering materials
journal contribution
posted on 2018-01-10, 00:00 authored by Kiara F Bruggeman, Richard WilliamsRichard Williams, David R NisbetTissue engineering scaffolds are designed to mimic physical, chemical, and biological features of the extracellular matrix, thereby providing a constant support that is crucial to improved regenerative medicine outcomes. Beyond mechanical and structural support, the next generation of these materials must also consider the more dynamic presentation and delivery of drugs or growth factors to guide new and regenerating tissue development. These two aspects are explored expansively separately, but they must interact synergistically to achieve optimal regeneration. This review explores common tissue engineering materials types, electrospun polymers and hydrogels, and strategies used for incorporating drug delivery systems into these scaffolds.
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Journal
Advanced healthcare materialsVolume
7Issue
1Article number
1700836Pagination
1 - 14Publisher
WileyLocation
London, Eng.Publisher DOI
eISSN
2192-2659Language
engPublication classification
C1 Refereed article in a scholarly journalUsage metrics
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drug deliveryelectrospinninghydrogelregenerative medicinetissue engineeringScience & TechnologyTechnologyEngineering, BiomedicalNanoscience & NanotechnologyMaterials Science, BiomaterialsEngineeringScience & Technology - Other TopicsMaterials ScienceMULTIFUNCTIONAL UNIMOLECULAR MICELLESTARGETED DRUG-DELIVERYNEURAL STEM-CELLSEXTRACELLULAR-MATRIXCONTROLLED-RELEASESCAFFOLDSNANOFIBERSDIFFERENTIATIONPROLIFERATIONNANOCOMPOSITES
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