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Effect of misoprostol on fat malabsorption in cystic fibrosis
journal contributionposted on 1988-01-01, 00:00 authored by P J Robinson, Peter Sly, A L Smith
Misoprostol, a synthetic prostaglandin that is known to reduce gastric acid production and stimulate duodenal bicarbonate production, was evaluated in 22 patients with cystic fibrosis. In those patients who had greater than 10% fat malabsorption while taking pancrease the addition of misoprostol significantly reduced the degree of fat malabsorption.