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Effects of an 18-month community-based, multifaceted, exercise program on patient-reported outcomes in older adults at risk of fracture: secondary analysis of a randomised controlled trial
journal contributionposted on 2023-05-19, 06:02 authored by Jason Talevski, Jenny GianoudisJenny Gianoudis, CA Bailey, PR Ebeling, Caryl NowsonCaryl Nowson, KD Hill, KM Sanders, Robin DalyRobin Daly
Summary: This study identified that an 18-month community-based, multifaceted, exercise program consisting of resistance, weight-bearing impact, and balance/mobility training combined with osteoporosis education and behavioural support can improve health-related quality of life (HRQoL) and osteoporosis knowledge in older adults at risk of fracture, but only for those adherent to the exercise regime. Purpose: To evaluate the effects of an 18-month community-based exercise, osteoporosis education and behaviour change program (Osteo-cise: Strong Bones for Life) on HRQoL, osteoporosis knowledge and osteoporosis health beliefs. Methods: This was a secondary analysis of an 18-month randomised controlled trial in which 162 older adults aged ≥ 60 years with osteopenia or increased falls/fracture risk were randomized to the Osteo-cise program (n = 81) or control group (n = 81). The program consisted of progressive resistance, weight-bearing impact and balance training (3 days/week); osteoporosis education to facilitate self-management of musculoskeletal health and behavioural support to enhance adherence to exercise. HRQoL, osteoporosis knowledge and osteoporosis health beliefs were assessed using the EuroQoL questionnaire (EQ-5D-3L), Osteoporosis Knowledge Assessment Tool and Osteoporosis Health Belief Scale, respectively. Results: Overall, 148 participants (91%) completed the trial. Mean exercise adherence was 55% and mean attendance for the three osteoporosis educational sessions ranged from 63-82%. After 12 and 18 months, there were no significant effects of the Osteo-cise program on HRQoL, osteoporosis knowledge or health beliefs relative to controls. Per protocol analyses (≥ 66% exercise adherence; n = 41) revealed a significant net benefit in EQ-5D-3L utility for the Osteo-cise group relative to controls after 12 months (P = 0.024) and 18 months (P = 0.029) and a significant net improvement in osteoporosis knowledge scores at 18 months (P = 0.014). Conclusion: This study supports the importance of adherence to exercise regimes, as adherence to the Osteo-cise: Strong Bones for Life program was associated with improvements in HRQoL and osteoporosis knowledge in older adults at increased risk for falls and fractures. Trial registration number: ACTRN12609000100291.
Publication classificationC1 Refereed article in a scholarly journal
Science & TechnologyLife Sciences & BiomedicineEndocrinology & MetabolismEducationExerciseFallsOsteoporosisPatient-reported outcomesQuality of lifeQUALITY-OF-LIFEHEALTHOSTEOPOROSISPREVENTIONADHERENCEWOMENFALLSEQ-5DPOWERHumansAgedQuality of LifeFractures, BoneExercise TherapyPatient Reported Outcome MeasuresRehabilitationPreventionClinical Trials and Supportive ActivitiesClinical ResearchAging7.1 Individual care needs7 Management of diseases and conditionsMusculoskeletalBiomedical Engineering not elsewhere classifiedPublic Health and Health Services not elsewhere classifiedClinical Sciences not elsewhere classified