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Effects of electroconvulsive therapy on regional cerebral blood flow measured by ⁹⁹m technetium HMPAO SPECT
journal contribution
posted on 2003-02-01, 00:00 authored by M D T Vangu, J D Esser, I H Boyd, Michael BerkMichael BerkDecreased cerebral blood flow is documented in depression. In this study, 15 patients were studied with 99mTc-HMPAO SPECT before and after a course of electroconvulsive therapy (ECT). Improvement in frontal and temporal hypoperfusion was seen only in those patients who responded to ECT. Cerebral hypoperfusion may be a state-dependent marker in depressive illness.
History
Journal
Progess in neuro-psychopharmacology & biological psychiatryVolume
27Issue
1Pagination
15 - 19Publisher
ElsevierLocation
Amsterdam, The NetherlandsPublisher DOI
ISSN
0278-5846Language
engPublication classification
C1.1 Refereed article in a scholarly journalCopyright notice
2002, Elsevier ScienceUsage metrics
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Categories
Keywords
AdultDepressive DisorderElectroconvulsive TherapyFemaleFrontal LobeHumansMaleMiddle AgedRadiopharmaceuticalsRegional Blood FlowTechnetium Tc 99m ExametazimeTemporal LobeTomography, Emission-Computed, Single-Photonmajor depressionorbitomeatal lineScience & TechnologyLife Sciences & BiomedicineClinical NeurologyNeurosciencesPharmacology & PharmacyPsychiatryNeurosciences & Neurologyregional cerebral blood flowPHOTON-EMISSION TOMOGRAPHYPREFRONTAL CORTEXDISEASEHYPOPERFUSIONPERFUSION