Effects of electroconvulsive therapy on regional cerebral blood flow measured by ⁹⁹m technetium HMPAO SPECT
Version 2 2024-05-30, 08:53
Version 1 2015-03-18, 11:13
journal contribution
posted on 2024-05-30, 08:53 authored by MDT Vangu, JD Esser, IH Boyd, Michael BerkMichael BerkDecreased cerebral blood flow is documented in depression. In this study, 15 patients were studied with 99mTc-HMPAO SPECT before and after a course of electroconvulsive therapy (ECT). Improvement in frontal and temporal hypoperfusion was seen only in those patients who responded to ECT. Cerebral hypoperfusion may be a state-dependent marker in depressive illness.
History
Journal
Progess in neuro-psychopharmacology & biological psychiatryVolume
27Article number
PII S0278-5846(02)00309-3Pagination
15-19Location
Amsterdam, The NetherlandsPublisher DOI
ISSN
0278-5846eISSN
1878-4216Language
engPublication classification
C1.1 Refereed article in a scholarly journalCopyright notice
2002, Elsevier ScienceIssue
1Publisher
ElsevierPublication URL
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Keywords
AdultDepressive DisorderElectroconvulsive TherapyFemaleFrontal LobeHumansMaleMiddle AgedRadiopharmaceuticalsRegional Blood FlowTechnetium Tc 99m ExametazimeTemporal LobeTomography, Emission-Computed, Single-Photonmajor depressionorbitomeatal lineScience & TechnologyLife Sciences & BiomedicineClinical NeurologyNeurosciencesPharmacology & PharmacyPsychiatryNeurosciences & Neurologyelectroconvulsive therapyregional cerebral blood flowPHOTON-EMISSION TOMOGRAPHYMAJOR DEPRESSIONPREFRONTAL CORTEXDISEASEHYPOPERFUSIONPERFUSION
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