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Enhanced photothermal therapy assisted with gold nanorods using a radially polarized beam

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journal contribution
posted on 2010-01-01, 00:00 authored by H Kang, B Jia, Jingliang LiJingliang Li, D Morrish, M Gu
We report on the use of a radially polarized beam for photothermal therapy of cancer cells labeled with gold nanorods. Due to a three-dimensionally distributed electromagnetic field in the focal volume, the radially polarized beam is proven to be a highly efficient laser mode to excite gold nanorods randomly oriented in cancer cells. As a result, the energy fluence for effective cancer cell damage is reduced to one fifth of that required for a linearly polarized beam, which is only 9.3% of the medical safety level.

History

Journal

Applied physics letters

Volume

96

Season

Article 063702

Pagination

1 - 4

Location

St Louis, Mo.

Open access

  • Yes

ISSN

0003-6951

eISSN

1077-3118

Language

eng

Publication classification

C1.1 Refereed article in a scholarly journal

Copyright notice

2010, American Institute of Physics

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