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Establishment of temperature control scheme for microbioreactor operation using integrated microheater

Version 2 2024-06-03, 12:40
Version 1 2014-10-28, 10:27
journal contribution
posted on 2024-06-03, 12:40 authored by A Zainal, A Moghadam, Abbas KouzaniAbbas Kouzani
This paper presents design and fabrication of a microbioreactor platform, and implementation of two temperature control methods (i.e. on-off and PID) and their performance evaluation on the microbioreactor platform (working volume ~300 μL). The temperature of the microbioreactor content is controlled by using a subminiature heater placed underneath the microbioreactor and is measured with a miniature Pt 100 sensor. The microbioreactor is also integrated with a magnetic stirring capacity and a water evaporation control scheme. Programs for the two temperature control methods are written in LabVIEW software and implemented by interfacing them with a data acquisition card. It is shown that by implementing on–off and PID temperature control methods, the temperature of the microbioreactor content can be tightly controlled with an accuracy of approximately ±0.5 °C of the set point values. Both control methods also provide a good response and settling time values (i.e. around 2 min). Contrary to the on/off control method, the PID control method requires no adjustments whenever the set-point values are modified. The PID temperature control method works well for the entire tested range.

History

Journal

Microsystem technologies

Volume

21

Pagination

415-428

Location

Berlin, Germany

ISSN

0946-7076

eISSN

1432-1858

Language

eng

Publication classification

C Journal article, C1 Refereed article in a scholarly journal

Copyright notice

2015, Springer

Issue

2

Publisher

Springer