File(s) under permanent embargo

Fabrication of boron nitride nanotube-gold nanoparticle hybrids using pulsed plasma in liquid

journal contribution
posted on 09.09.2014, 00:00 authored by Sri Balaji Ponraj, Frank ChenFrank Chen, Luhua LiLuhua Li, J S Shankaranarayanan, Gayathri Devi Rajmohan, J du Plessis, Andrew SinclairAndrew Sinclair, Ying (Ian) ChenYing (Ian) Chen, Xungai WangXungai Wang, Jagat Kanwar, Xiujuan Dai
Plasma, generated in liquid at atmospheric pressure by a nanosecond pulsed voltage, was used to fabricate hybrid structures from boron nitride nanotubes and gold nanoparticles in deionized water. The pH was greatly reduced, conductivity was significantly increased, and concentrations of reactive oxygen and nitrogen species in the water were increased by the plasma treatment. The treatment reduced the length of the nanotubes, giving more individual cuplike structures, and introduced functional groups onto the surface. Gold nanoparticles were successively assembled onto the functionalized surfaces. The reactive species from the liquid plasma along with the nanosecond pulsed electric field seem to play a role in the shortening and functionalization of the nanotubes and the assembly of gold nanoparticles. The potential for targeted drug delivery was tested in a preliminary investigation using doxorubicin-loaded plasma-treated nanotubes which were effective at killing ∼99% of prostate cancer cells.

History

Journal

Langmuir

Volume

30

Issue

35

Pagination

10712 - 10720

Publisher

American Chemical Society

Location

Washington, DC

ISSN

0743-7463

eISSN

1520-5827

Language

eng

Publication classification

C Journal article; C1 Refereed article in a scholarly journal

Copyright notice

2014, American Chemical Society