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Facial Preparation of Cyclometalated Iridium (III) Nanowires as Highly Efficient Electrochemiluminescence Luminophores for Biosensing
journal contribution
posted on 2023-05-22, 02:45 authored by Y Huang, Egan DoevenEgan Doeven, L Chen, Y Yao, Y Wang, B Lin, Y Zeng, L Li, Z Qian, L GuoIn this study, highly efficient ECL luminophores composed of iridium complex-based nanowires (Ir–NCDs) were synthesized via covalently linking bis(2-phenylpyridine)-(4-carboxypropyl-2,2′-bipyridyl) iridium(III) hexafluorophosphate with nitrogen-doped carbon quantum dots (NCDs). The ECL intensity of the nanowires showed a five-fold increase in ECL intensity compared with the iridium complex monomer under the same experimental conditions. A label-free ECL biosensing platform based on Ir–NCDs was established for Salmonella enteritidis (SE) detection. The ECL signal was quenched linearly in the range of 102–108 CFU/mL for SE with a detection limit of 102 CFU/mL. Moreover, the relative standard deviations (RSD) of the stability within and between batches were 0.98% and 3.9%, respectively. In addition, the proposed sensor showed high sensitivity, selectivity and stability towards SE in sheep feces samples with satisfactory results. In summary, the excellent ECL efficiency of Ir–NCDs demonstrates the prospects for Ir(III) complexes in bioanalytical applications.
History
Journal
BiosensorsVolume
13Article number
ARTN 459Location
SwitzerlandPublisher DOI
ISSN
2079-6374eISSN
2079-6374Language
EnglishPublication classification
C1 Refereed article in a scholarly journalIssue
4Publisher
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Keywords
Science & TechnologyPhysical SciencesTechnologyChemistry, AnalyticalNanoscience & NanotechnologyInstruments & InstrumentationChemistryScience & Technology - Other Topicselectrochemiluminescenceiridium(III) nanowirebiosensingSalmonella enteritidisSALMONELLA-ENTERICAAMPLIFICATIONENTERITIDISASSAYAnimalsSheepNanowiresIridiumCarbonPhotometryLuminescent MeasurementsBiosensing TechniquesElectrochemical TechniquesAnalytical Chemistry not elsewhere classifiedBiochemistry and Cell Biology not elsewhere classified
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