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Facile and versatile solid state surface modification of silk fibroin membranes using click chemistry
journal contributionposted on 2018-01-01, 00:00 authored by L Raynal, Ben AllardyceBen Allardyce, Xungai Wang, R J Dilley, Rangam RajkhowaRangam Rajkhowa, Luke HendersonLuke Henderson
Reported is a fast and versatile protocol to surface modify pre-cast silk membranes targeting tyrosine residues. Enriched alkyne silk membranes were prepared using this method and azides possessing a range of functional groups were tethered to the membrane surface using click chemistry to give a range of water contact angles from 85 ± 3° to 34 ± 6°.