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Falls in community-dwelling women with bipolar disorder: a case–control study

Version 3 2024-06-19, 15:33
Version 2 2024-06-04, 07:15
Version 1 2023-02-10, 04:30
journal contribution
posted on 2024-06-19, 15:33 authored by Amanda StuartAmanda Stuart, Julie PascoJulie Pasco, Michael BerkMichael Berk, Shae QuirkShae Quirk, H Koivumaa-Honkanen, R Honkanen, Mohammadreza MohebbiMohammadreza Mohebbi, Lana WilliamsLana Williams
Abstract Background Falls are a common occurrence in psychiatric hospital settings, however population-based research among individuals with psychiatric disorders, in particular bipolar disorder (BD) is scant. Thus, we aimed to investigate falls risk in community-dwelling women diagnosed with BD. Methods Women with BD (cases, n = 119) were recruited from health care settings located in southeast Victoria, Australia. Age-matched controls (n = 357, ratio 3:1) without BD were participants in the Geelong Osteoporosis Study drawn from the same geographical region. Lifetime history of BD was identified by semi-structured clinical interview (SCID-IV/NP). Previous 12-month falls data were obtained via questionnaire. Information on mobility, alcohol use, general health, medication use, blood pressure, body mass index, socioeconomic status and use of a walking aid was collected. Generalised Estimating Equations, binary and ordinal logistic regression were used to determine the odds ratio (OR) and 95% confidence interval (CI) for falls following adjustment for confounders. Results During the 12-month period, 34 (28.6%, median age 48.4 yr) cases and 70 (19.6%, median age 49.1 yr) controls reported one fall; 22 (18.5%) cases and 18 (5.0%) controls reported ≥ two falls (p < 0.001). Cases had 2.5-fold increased odds of at least one fall and 2.9-fold increased likelihood of increasing falls categories (0 vs. 1 vs. 2 +), compared to controls [adjOR 2.5, 95%CI (1.8, 3.4), adjOR OR 2.9, 95%CI (2.0, 4.1)]. Conclusion Risk of falls was greater among women with BD. Balance training could be a research and clinical focus for falls prevention programs among women with bipolar disorder to prevent the detrimental outcomes associated with falling.

History

Journal

BMC Psychiatry

Volume

22

Article number

ARTN 620

Location

England

ISSN

1471-244X

eISSN

1471-244X

Language

English

Publication classification

C1 Refereed article in a scholarly journal

Issue

1

Publisher

BMC