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Fatty acid composition in tissues of mice fed diets containing conjugated linolenic acid and conjugated linoleic acid

journal contribution
posted on 2009-05-01, 00:00 authored by G F Yuan, Andrew SinclairAndrew Sinclair, H Y Sun, D Li
The influence of 1% alpha-eleostearic acid (α-ESA, cis9,trans11,trans 13-18:3) and 1% punicic acid (PA, cis9,trans11,cis13-18:3) on fatty acid composition in mouse tissues was compared with conjugated linoleic acid (CLA, mixture of primarily cis9,trans11- and trans10,cis12-18:2) in the present study. The content (% total fatty acids) of 18:2n-6 was significantly reduced in the heart and adipose tissues, and total polyunsaturated fatty acids (PUFAs) and n-6 PUFA were significantly reduced in adipose tissue by α-ESA, PA and CLA feeding. The content of 22:6n-3 and total n-3 PUFA were significantly increased in the liver, kidney and heart by PA feeding, but not by α-ESA. In contrast to PA, supplementation with CLA significantly decreased 22:6n-3 in the liver, kidney and heart. The content of 20:4n-6 was significantly decreased in the liver and kidney by CLA feeding, but not by α-ESA and PA. The present results indicate that α-ESA, PA and CLA have differential effects on 22:6n-3 and 20:4n-6 content in mouse tissues.

History

Journal

Journal of food lipids

Volume

16

Issue

2

Pagination

148 - 163

Publisher

Wiley-Blackwell Publishing

Location

Oxford, England

ISSN

1065-7258

eISSN

1745-4522

Language

eng

Publication classification

C1 Refereed article in a scholarly journal

Copyright notice

2009, Wiley Periodicals, Inc.