Fe-bLf nanoformulation targets survivin to kill colon cancer stem cells and maintains absorption of iron, calcium and zinc
Version 2 2024-06-07, 00:33Version 2 2024-06-07, 00:33
Version 1 2015-03-17, 15:10Version 1 2015-03-17, 15:10
journal contribution
posted on 2024-06-07, 00:33authored byJR Kanwar, V Mahidhara, K Roy, S Sasidharan, S Krishnakumar, N Prasad, R Sehgal, RK Kanwar
To validate the anticancer efficacy of alginate-enclosed, chitosan-conjugated, calcium phosphate, iron-saturated bovine lactoferrin (Fe-bLf) nanocarriers/nanocapsules (NCs) with improved sustained release and ability to induce apoptosis by downregulating survivin, as well as cancer stem cells.