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Fish oil and multivitamin supplementation reduces oxidative stress but not inflammation in healthy older adults: a randomised controlled trial

journal contribution
posted on 2015-12-01, 00:00 authored by A Pipingas, Andrew SinclairAndrew Sinclair, K D Croft, A S Januszewski, A J Jenkins, T A Mori, R Cockerell, N A Grima, C Stough, A Scholey, S P Myers, A Sali, M P Pase
The effects of daily fish oil supplementation, with and without multivitamins, on biochemical markers of health were examined. Healthy adults (N = 160) were randomised to receive 3 g of salmon oil with a multivitamin, 6 g of salmon oil with a multivitamin, 6 g of salmon oil in isolation or placebo in a double-blind fashion on a daily basis for 16 weeks. Relative to placebo, both 6 g salmon oil groups displayed significantly lower F2-isoprostane levels at endpoint. Increases in red blood cell polyunsaturated fatty acids correlated with reductions in F2-isoprostanes. Treatment had no effect on inflammatory cytokines, C-reactive protein, fibrinogen, cholesterol or triacylglycerol.

History

Journal

Journal of functional foods

Volume

19

Issue

Part B

Pagination

949 - 957

Publisher

Elsevier

Location

Amsterdam, The Netherlands

ISSN

1756-4646

Language

eng

Publication classification

C Journal article; C1 Refereed article in a scholarly journal

Copyright notice

2014, Elsevier