From genetic to postgenomic determinisms: The role of the environment reconsidered

Abstract In the past twenty years, conceptual and technological shifts in the life sciences have unseated the causal primacy of the gene. The picture emerging from ‘postgenomic’ science is one that emphasises multifactorial dependencies between the environment, development, and the genome, and blurs boundaries between biological individuals, and between the body and the environment. Despite the rejection of genetic determinism within postgenomics, forms of determinism nevertheless persist. The environment is often conceptualised in postgenomic research in a narrow and constrained way, affording an outsized causal role to certain environmental factors while neglecting the influence of others. This carries ethical and social implications, including for understandings of race and motherhood. This topical collection interrogates the environmental determinisms developing within postgenomic science, through investigation of their conceptual foundations, histories, and social contexts across a range of postgenomic fields.