File(s) under permanent embargo
Fucoidan-based nanostructures: A focus on its combination with chitosan and the surface functionalization of metallic nanoparticles for drug delivery
journal contribution
posted on 2020-02-15, 00:00 authored by Phuong TranPhuong Tran, Wei DuanWei Duan, T T D Tran© 2019 Elsevier B.V. Although fucoidan (FU) shows potential bioactivity against various diseases, it has also been demonstrated to be an excellent material for nanodelivery. FU can be utilized to prepare nanoparticles for drug loading or to stabilize nanoparticles and is often incorporated into nanostructure materials to extend or maximize its role in theranostics applications. This review discusses strategies involving FU and other material combinations used as nanostructures for biomedical applications with a focus on chitosan-FU mixtures for oral delivery and FU-based surface functionalization for targeting and theranostics. The ability of FU to form different nanostructures is also reviewed. Moreover, various types and mechanisms of combinations involving FU-based nanostructures are discussed. A discussion of the current outlook and future studies provides ideas for more efficacious methods for FU-based nanoparticles and could enable their utilization in clinical trials.
History
Journal
International Journal of PharmaceuticsVolume
575Article number
118956Pagination
1 - 8Publisher
ElsevierLocation
Amsterdam, The NetherlandsPublisher DOI
ISSN
0378-5173eISSN
1873-3476Language
engPublication classification
C1 Refereed article in a scholarly journalUsage metrics
Categories
No categories selectedKeywords
Fucoidan-based nanostructuresNanoparticlesTheranosticsSurface functionalizationMetallic nanoparticlesScience & TechnologyLife Sciences & BiomedicinePharmacology & PharmacyIRON-OXIDE NANOPARTICLESBOVINE SERUM-ALBUMINGOLD NANOPARTICLESP-SELECTINCHITOSAN\/FUCOIDAN NANOPARTICLESMULTILAYER NANOCAPSULESSULFATED POLYSACCHARIDESOLID DISPERSIONSGREEN SYNTHESISORAL DELIVERY
Licence
Exports
RefWorks
BibTeX
Ref. manager
Endnote
DataCite
NLM
DC