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Functionality of fatty acid chemoreception : a potential factor in the development of obesity?

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journal contribution
posted on 2013-01-01, 00:00 authored by Lisa Newman, R Haryono, Russell KeastRussell Keast
Excess dietary fat consumption is recognized as a strong contributing factor in the development of overweight and obesity. Understanding why some individuals are better than others at regulating fat intake will become increasingly important and emerging associative evidence implicates attenuated fatty acid sensing in both the oral cavity and gastrointestinal (GI) tract in the development of obesity. Functional implications of impaired fatty acid chemoreception include diminished activation of the gustatory system, the cephalic response and satiety. This review will focus on knowledge from animal and human studies supporting the existence of oral fatty acid chemoreception including putative oral detection mechanisms, and how sensitivity to fatty acids is associated with fat consumption and fatty food preference.

History

Journal

Nutrients

Volume

5

Pagination

1287 - 1300

Location

Basel,Switzerland

Open access

  • Yes

ISSN

2072-6643

Language

eng

Publication classification

C1 Refereed article in a scholarly journal

Copyright notice

2013, MDPI