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Gender-based time discrepancy in diagnosis of coronary artery disease based on data analytics of electronic medical records
journal contribution
posted on 2023-02-20, 22:52 authored by M Panahiazar, AM Bishara, Y Chern, Roohallah AlizadehsaniRoohallah Alizadehsani, Shariful IslamShariful Islam, D Hadley, R Arnaout, RE BeyguiBackground: Women continue to have worse Coronary Artery Disease (CAD) outcomes than men. The causes of this discrepancy have yet to be fully elucidated. The main objective of this study is to detect gender discrepancies in the diagnosis and treatment of CAD. Methods: We used data analytics to risk stratify ~32,000 patients with CAD of the total 960,129 patients treated at the UCSF Medical Center over an 8 year period. We implemented a multidimensional data analytics framework to trace patients from admission through treatment to create a path of events. Events are any medications or noninvasive and invasive procedures. The time between events for a similar set of paths was calculated. Then, the average waiting time for each step of the treatment was calculated. Finally, we applied statistical analysis to determine differences in time between diagnosis and treatment steps for men and women. Results: There is a significant time difference from the first time of admission to diagnostic Cardiac Catheterization between genders (p-value = 0.000119), while the time difference from diagnostic Cardiac Catheterization to CABG is not statistically significant. Conclusion: Women had a significantly longer interval between their first physician encounter indicative of CAD and their first diagnostic cardiac catheterization compared to men. Avoiding this delay in diagnosis may provide more timely treatment and a better outcome for patients at risk. Finally, we conclude by discussing the impact of the study on improving patient care with early detection and managing individual patients at risk of rapid progression of CAD.
History
Journal
Frontiers in Cardiovascular MedicineVolume
9Article number
ARTN 969325Location
SwitzerlandPublisher DOI
ISSN
2297-055XeISSN
2297-055XLanguage
EnglishPublication classification
C1 Refereed article in a scholarly journalPublisher
FRONTIERS MEDIA SAUsage metrics
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No categories selectedKeywords
Science & TechnologyLife Sciences & BiomedicineCardiac & Cardiovascular SystemsCardiovascular System & Cardiologycardiac catheterizationcoronary artery bypass grafting (CABG)gender-based discrepanciesCoronary Artery Diseasebig dataelectronic medical recordRISK-FACTORSCARDIOVASCULAR-DISEASEBiomedical ImagingClinical ResearchCardiovascularHeart DiseaseAtherosclerosisHeart Disease - Coronary Heart Disease4.2 Evaluation of markers and technologies4.1 Discovery and preclinical testing of markers and technologies4 Detection, screening and diagnosis
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