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Genetic and epigenetic variation in vulvar cancer: Current research and future clinical practice
journal contribution
posted on 2022-11-29, 23:29 authored by Rebekah McWhirterRebekah McWhirter, J R Marthick, J A Boyle, J L DickinsonVulvar cancer is a relatively rare gynaecological malignancy, the treatment of which is associated with significant patient morbidity. With reports that the incidence of vulvar cancer is increasing, there is a rising need for improved preventive, diagnostic and therapeutic tools. Recent advances within genetics and epigenetics present possible approaches for addressing this need, by contributing to the clari fication of the aetiology of this disease, identifying screening and drug targets and introducing the potential for personalised treatments. This paper reviews the genetic and epigenetic research undertaken to date within vulvar cancer, evaluates its potential for clinical application and identifies directions for future research.
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Journal
Australian and New Zealand Journal of Obstetrics and GynaecologyVolume
54Pagination
406 - 411Publisher DOI
ISSN
0004-8666eISSN
1479-828XPublication classification
C1 Refereed article in a scholarly journal; C1.1 Refereed article in a scholarly journalUsage metrics
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