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Download fileGenetic polymorphisms in glutathione-S-transferases are associated with anxiety and mood disorders in nicotine dependence
journal contribution
posted on 2014-06-01, 00:00 authored by S Odebrecht Vargas Nunes, M R Pizzo de Castro, M A Ehara Watanabe, R Losi Guembarovski, H Odebrecht Vargas, E M Reiche, H Kaminami Morimoto, Seetal DoddSeetal Dodd, Michael BerkMichael BerkNicotine dependence is associated with an increased risk of mood and anxiety disorders and suicide. The primary hypothesis of this study was to identify whether the polymorphisms of two glutathione-S-transferase enzymes (GSTM1 and GSTT1 genes) predict an increased risk of mood and anxiety disorders in smokers with nicotine dependence.
History
Journal
Psychiatric geneticsVolume
24Issue
3Pagination
87 - 93Publisher
Lippincott Williams & WilkinsLocation
Philadelphia, PAPublisher DOI
eISSN
1473-5873Language
engPublication classification
C Journal article; C1 Refereed article in a scholarly journalCopyright notice
2014, The AuthorsUsage metrics
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Categories
Keywords
AdolescentAdultAnxiety DisordersFemaleGenetic Predisposition to DiseaseGlutathione TransferaseHumansMaleMiddle AgedMood DisordersPolymorphism, GeneticSmokingSuicide, AttemptedTobacco Use DisorderYoung AdultScience & TechnologyLife Sciences & BiomedicineGenetics & HeredityNeurosciencesNeurosciences & Neurologymood disorderanxiety disordernicotine dependencegenetic polymorphismsglutathione-S-transferaseMAJOR DEPRESSIVE DISORDERCORONARY-HEART-DISEASECIGARETTE-SMOKINGOXIDATIVE STRESSPSYCHIATRIC-DISORDERSSUICIDAL-BEHAVIORTOBACCO SMOKINGINFLAMMATORY MARKERSBIPOLAR DISORDERMENTAL-HEALTH