Genetic polymorphisms in glutathione-S-transferases are associated with anxiety and mood disorders in nicotine dependence
Version 3 2024-06-17, 10:29
Version 2 2024-05-30, 15:25
Version 1 2015-02-05, 14:11
journal contribution
posted on 2024-06-17, 10:29 authored by S Odebrecht Vargas Nunes, MR Pizzo de Castro, MA Ehara Watanabe, R Losi Guembarovski, H Odebrecht Vargas, EM Reiche, H Kaminami Morimoto, Seetal DoddSeetal Dodd, Michael BerkMichael BerkNicotine dependence is associated with an increased risk of mood and anxiety disorders and suicide. The primary hypothesis of this study was to identify whether the polymorphisms of two glutathione-S-transferase enzymes (GSTM1 and GSTT1 genes) predict an increased risk of mood and anxiety disorders in smokers with nicotine dependence.
History
Journal
Psychiatric geneticsVolume
24Pagination
87-93Location
Philadelphia, PAPublisher DOI
Open access
- Yes
ISSN
0955-8829eISSN
1473-5873Language
engPublication classification
C Journal article, C1 Refereed article in a scholarly journalCopyright notice
2014, Lippincott Williams and WilkinsIssue
3Publisher
Lippincott Williams & WilkinsPublication URL
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Keywords
AdolescentAdultAnxiety DisordersFemaleGenetic Predisposition to DiseaseGlutathione TransferaseHumansMaleMiddle AgedMood DisordersPolymorphism, GeneticSmokingSuicide, AttemptedTobacco Use DisorderYoung AdultScience & TechnologyLife Sciences & BiomedicineGenetics & HeredityNeurosciencesNeurosciences & Neurologymood disorderanxiety disordernicotine dependencegenetic polymorphismsglutathione-S-transferaseMAJOR DEPRESSIVE DISORDERCORONARY-HEART-DISEASECIGARETTE-SMOKINGOXIDATIVE STRESSPSYCHIATRIC-DISORDERSSUICIDAL-BEHAVIORTOBACCO SMOKINGINFLAMMATORY MARKERSBIPOLAR DISORDERMENTAL-HEALTHSchool of MedicineInnovation in Mental and Physical Health and Clinical Treatment920414 Substance Abuse110319 Psychiatry (incl Psychotherapy)111714 Mental Health920410 Mental HealthFaculty of Health
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