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HD-FFQ to Detect Nutrient Deficiencies and Toxicities for a Multiethnic Asian Dialysis Population

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posted on 2025-01-23, 05:01 authored by Mohammad Syafiq Md Ali, Zu-Wei Yeak, Ban-Hock Khor, Sharmela Sahathevan, Ayesha SualeheenAyesha Sualeheen, Jun-Hao Lim, Nurul Iman Hafizah Adanan, Abdul Halim Abdul Gafor, Nor Fadhlina Zakaria, Pramod Khosla, Tilakavati Karupaiah, Zulfitri Azuan Mat Daud
A rapid and reliable tool appropriate to quantifying macronutrient and micronutrient intakes in diets consumed by Malaysian hemodialysis (HD) patients is lacking. We aimed to develop and validate a novel HD-food frequency questionnaire (HD-FFQ) to assess habitual nutritional intakes of HD patients with diverse ethnic backgrounds. This study was conducted in three phases. In Phase I, a HD-FFQ comprising 118 food items was developed using 3-day diet recalls (3DDR) from 388 HD patients. Phase II was the face and content validation using the Scale-Content Validity Index (S-CVI). After successfully developing the FFQ, Phase III tested relative validation against a reference method, the 3DDR. Results from Phase III showed that the mean difference for absolute intakes of nutrients assessed by HD-FFQ and 3DDR were significant (p < 0.05). However, there was a significant correlation between the HD-FFQ and reference method ranging from 0.35–0.47 (p < 0.05). Cross-quartile classification showed that <10% of patients were grossly misclassified. In conclusion, the HD-FFQ has an acceptable relative validity in assessing and ranking the dietary intake of the HD patients in Malaysia.

History

Journal

Nutrients

Volume

12

Article number

1585

Pagination

1-16

Location

Basel, Switzerland

Open access

  • Yes

ISSN

2072-6643

eISSN

2072-6643

Language

eng

Publication classification

C1.1 Refereed article in a scholarly journal

Issue

6

Publisher

MDPI