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HDL and cancer - causality still needs to be confirmed? Update 2020

journal contribution
posted on 2024-07-08, 00:58 authored by Shiva GanjaliShiva Ganjali, M Banach, M Pirro, Z Fras, A Sahebkar
An inverse correlation between high-density lipoprotein cholesterol (HDL-C) and cancer risk has been shown by several epidemiological studies. Some studies have even suggested that HDL-C can be used as a prognostic marker in patients with certain types of cancer. However, whether reduced HDL-C level is a consequential or causal factor in the development and progression of cancer remains a controversial issue. In this review, we update and summarize recent advances that highlight the role of HDL and some of its components in prognosis, diagnosis and treatment of cancer.

History

Journal

Seminars in Cancer Biology

Volume

73

Pagination

169-177

Location

Amsterdam, The Netherlands

Open access

  • No

ISSN

1044-579X

eISSN

1096-3650

Language

eng

Publication classification

C1.1 Refereed article in a scholarly journal

Publisher

Elsevier