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Health impacts of eicosapentaenoic acid and docosahexaenoic acid

journal contribution
posted on 2013-01-01, 00:00 authored by H Mateos, Paul Lewandowski, Vanessa VaughanVanessa Vaughan, X Su
Long chain omega-3 polyunsaturated fatty acids (LC n-3 PUFA) particularly, eicosapentaenoic acid (EPA, 22: 5n-3) and docosahexaenoic acid (DHA, 22: 6n-3) have been reported to reduce the risks of cardiovascular disease (CVD) including myocardial infarction, stroke, coronary artery disease and sudden cardiac death. In addition, these fatty acids play an important role in reduction of cancer risks, Alzheimer's disease, depression and schizophrenia. Furthermore, studies also showed that EPA and DHA are important for foetal development, particularly neuronal and retinal functions. Several recent human trials have strengthened the evidence that EPA and DHA can reduce the risks of various chronic diseases although this has not been a uniform finding. In general, the high prevalence of mortality caused by chronic disease can be prevented by consumption of LC n-3 PUFA, which has been proven to have considerable health benefits. The aim of this paper was to review main scientific evidence regarding the health impact of LC n-3 PUFA, especially EPA and DHA on chronic disease including CVD, cancer, mental health, arthritis and infant development.

History

Journal

CAB reviews : perspectives in agriculture, veterinary science, nutrition and natural resources

Volume

8

Issue

7

Pagination

1 - 12

Publisher

CABI

Location

Oxfordshire, England

ISSN

1749-8848

Language

eng

Publication classification

C1 Refereed article in a scholarly journal

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