islam-howtounravelthekey-2021.pdf (2.19 MB)
How to unravel the key functions of cryptic oomycete elicitin proteins and their role in plant disease
journal contribution
posted on 2021-06-01, 00:00 authored by Aayushree KharelAayushree Kharel, Md Tohidul IslamMd Tohidul Islam, Jim RookesJim Rookes, David CahillDavid CahillPathogens and plants are in a constant battle with one another, the result of which is either the restriction of pathogen growth via constitutive or induced plant defense responses or the pathogen colonization of plant cells and tissues that cause disease. Elicitins are a group of highly conserved proteins produced by certain oomycete species, and their sterol binding ability is recognized as an important feature in sterol–auxotrophic oomycetes. Elicitins also orchestrate other aspects of the interactions of oomycetes with their plant hosts. The function of elicitins as avirulence or virulence factors is controversial and is dependent on the host species, and despite several decades of research, the function of these proteins remains elusive. We summarize here our current understanding of elicitins as either defense-promoting or defense-suppressing agents and propose that more recent approaches such as the use of ‘omics’ and gene editing can be used to unravel the role of elicitins in host–pathogen interactions. A better understanding of the role of elicitins is required and deciphering their role in host–pathogen interactions will expand the strategies that can be adopted to improve disease resistance and reduce crop losses.
History
Journal
PlantsVolume
10Issue
6Article number
1201Pagination
1 - 12Publisher
MDPILocation
Basel, SwitzerlandPublisher DOI
Link to full text
ISSN
2223-7747eISSN
2223-7747Language
EnglishPublication classification
C Journal article; C1 Refereed article in a scholarly journalUsage metrics
Categories
Keywords
avirulenceelicitinsLife Sciences & BiomedicineomicsoomycetesPhytophthoraPlant Sciencesplant-pathogen interactionScience & TechnologyvirulenceCRISPR\/CasCRISPRCasCELL-WALL PROTEINSPHYTOPHTHORA-CINNAMOMICAUSAL AGENTCRISPR-CASGENERESISTANCEIDENTIFICATIONINDUCTIONDIAGNOSISINFESTANSplant–pathogen interactionPlant Biology
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