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Human serum biomarker detection based on a cascade signal amplification strategy by a DNA molecule machine

journal contribution
posted on 2015-07-11, 00:00 authored by Jing Liu, Xiaoyan Xin, Hong Zhou, Shusheng Zhang
A convenient method is presented that employs a DNA machine for protein biomarker detection. The detection limit is 400 times lower compared to the method without a DNA machine. This study provides a promising method that could realize most protein biomarker detections without the corresponding aptamers, using a DNA machine for signal amplification.

History

Journal

Chemical communications

Volume

51

Issue

54

Pagination

10843 - 10846

Publisher

Royal Society of Chemistry

Location

Cambridge, Eng.

ISSN

1359-7345

eISSN

1364-548X

Language

eng

Publication classification

C1.1 Refereed article in a scholarly journal

Copyright notice

2015, The Royal Society of Chemistry

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