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Hypoglycaemia symptom frequency, severity, burden, and utility among adults with type 1 diabetes and impaired awareness of hypoglycaemia: Baseline and 24 weeks findings from the HypoCOMPaSS study

journal contribution
posted on 2023-10-12, 03:17 authored by Uffe Søholm, Elizabeth Holmes‐Truscott, Melanie Broadley, Stephanie A Amiel, Christel HendrieckxChristel Hendrieckx, Pratik Choudhary, Frans Pouwer, James AM Shaw, Jane SpeightJane Speight
AbstractAimsTo determine the frequency, severity, burden, and utility of hypoglycaemia symptoms among adults with type 1 diabetes (T1D) and impaired awareness of hypoglycaemia (IAH) at baseline and week 24 following the HypoCOMPaSS awareness restoration intervention.MethodsAdults (N=96) with T1D (duration: 29±12 years; 64% women) and IAH completed the HypoBurden Questionnaire (HypoB‐Q), assessing experience of 20 pre‐specified hypoglycaemia symptoms, at baseline and Week 24.ResultsAt baseline, 93 (97%) participants experienced at least one symptom (mean±SD 10.6±4.6 symptoms). The proportion recognising each specific symptom ranged from 15‐83%. At 24 weeks, symptom severity and burden appear reduced, and utility increased.ConclusionsAdults with T1D and IAH experience a range of hypoglycaemia symptoms. Perceptions of symptom burden or utility are malleable. Although larger scale studies are needed to confirm, these findings suggest that changing the salience of the symptomatic response may be more important in recovering protection from hypoglycaemia through regained awareness than intensifying symptom frequency or severity.

History

Journal

Diabetic Medicine

Article number

15231

Pagination

e15231-

Location

England

ISSN

0742-3071

eISSN

1464-5491

Language

en

Publisher

Wiley

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