Intra-aortic mural thrombosis and splenic infarction in association with ulcerative colitis

Background: Arterial thrombosis is a very rare, but recognised complication of inflammatory bowel disease that can result in significant morbidity and mortality. Case presentation We present the case of a 48-year-old female with previously well-controlled ulcerative colitis who presented with severe left upper quadrant abdominal pain. Imaging investigations subsequently revealed a large intra-aortic mural thrombus extending into the coeliac axis complicated by splenic infarction. This occurred in the absence of other prothrombotic states such as thrombo-philias or vasculitis. Conclusion This case highlights the frequently overlooked association between inflammatory bowel disease and arterial thrombosis. © Royal Academy of Medicine in Ireland 2010.