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Ketamine and rapidly acting antidepressants: breaking the speed of sound or light?
journal contribution
posted on 2018-11-01, 00:00 authored by Michael BerkMichael Berk, Collen Loo, Christopher G Davey, Brian H HarveyThere is an urgent need for rapidly acting antidepressants. Current therapies share a delayed onset of action, contrasting with drugs of abuse that have rapid psychotropic effects but cause tolerance and dependence. A key uncertainty is whether there is a finite speed limit imposed by the critical role of homeostatic adaptive mechanisms that underpin the efficacy and onset of available psychotropic agents and whether this is mutable with emerging agents with potential rapid onset, in particular ketamine.
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Journal
Australian and New Zealand journal of psychiatryVolume
52Issue
11Pagination
1026 - 1029Publisher
SAGE PublicationsLocation
London, Eng.Publisher DOI
eISSN
1440-1614Language
engPublication classification
C1 Refereed article in a scholarly journalCopyright notice
2018, The Royal Australian and New Zealand College of PsychiatristsUsage metrics
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