Lipid and insulin infusion-induced skeletal muscle insulin resistance is likely due to metabolic feedback and not changes in IRS-1, Akt or AS160 phosphorylation

Hoy, A; Brandon, A; Turner, N; Watt, Matthew; Bruce, Clinton; Cooney, G; Kraegen, E

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Lipid and insulin infusion-induced skeletal muscle insulin resistance is likely due to metabolic feedback and not changes in IRS-1, Akt or AS160 phosphorylation

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posted on 2009-07-01, 00:00 authored by A Hoy, A Brandon, N Turner, Matthew Watt, Clinton BruceClinton Bruce, G Cooney, E Kraegen

Lipid and insulin infusion-induced skeletal muscle insulin resistance is likely due to metabolic feedback and not changes in IRS-1, Akt or AS160 phosphorylation

History

Journal

American journal of physiology : endocrinology and metabolism

Volume

297

Issue

1

Publisher

American Physiological Society

Location

Bethesda, Maryland

Publisher DOI

https://doi.org/10.1152/ajpendo.90945.2008

ISSN

0193-1849

eISSN

1522-1555

Language

eng

Publication classification

C1.1 Refereed article in a scholarly journal

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Keywords

hyperlipidemia in vivo metabolism lipotoxicity long-chain acyl-CoA pyruvate dehydrogenase kinase 4 Science & Technology Life Sciences & Biomedicine Endocrinology & Metabolism Physiology FREE FATTY-ACIDS PROTEIN-KINASE-B PYRUVATE-DEHYDROGENASE ACYL-COA RECEPTOR SUBSTRATE-1 RAT SKELETAL CERAMIDE ACCUMULATION GLUCOSE-METABOLISM GENE-EXPRESSION INDUCED OBESITY

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File(s) under permanent embargo

Lipid and insulin infusion-induced skeletal muscle insulin resistance is likely due to metabolic feedback and not changes in IRS-1, Akt or AS160 phosphorylation

History

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Publisher

Location

Publisher DOI

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