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Malaria Molecular Epidemiology: Lessons from the International Centers of Excellence for Malaria Research Network

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journal contribution
posted on 2015-09-02, 00:00 authored by A A Escalante, M U Ferreira, J M Vinetz, S K Volkman, L Cui, D Gamboa, D J Krogstad, Alyssa BarryAlyssa Barry, J M Carlton, A M A van Eijk, K Pradhan, I Mueller, B Greenhouse, M A Pacheco, A F Vallejo, S Herrera, I Felger
© The American Society of Tropical Medicine and Hygiene. Molecular epidemiology leverages genetic information to study the risk factors that affect the frequency and distribution of malaria cases. This article describes molecular epidemiologic investigations currently being carried out by the International Centers of Excellence for Malaria Research (ICEMR) network in a variety of malaria-endemic settings. First, we discuss various novel approaches to understand malaria incidence and gametocytemia, focusing on Plasmodium falciparum and Plasmodium vivax. Second, we describe and compare different parasite genotyping methods commonly used in malaria epidemiology and population genetics. Finally, we discuss potential applications of molecular epidemiological tools and methods toward malaria control and elimination efforts.

History

Journal

The American journal of tropical medicine and hygiene

Volume

93

Issue

3

Pagination

79 - 86

Publisher

American Society of Tropical Medicine and Hygiene

Location

Northbrook, Ill.

ISSN

1476-1645

Language

eng

Publication classification

C1 Refereed article in a scholarly journal