hiam-mappingrobustgenetic-2021.pdf (271.01 kB)
Download fileMapping robust genetic variants associated with exercise responses
journal contribution
posted on 2021-01-01, 00:00 authored by J Alvarez-Romero, S Voisin, N Eynon, Danielle HiamDanielle HiamThis review summarised robust and consistent genetic variants associated with
aerobic-related and resistance-related phenotypes. In total we highlight 12 SNPs
and 7 SNPs that are robustly associated with variance in aerobic-related and
resistance-related phenotypes respectively. To date, there is very little
literature ascribed to understanding the interplay between genes and
environmental factors and the development of physiological traits. We discuss
future directions, including large-scale exercise studies to elucidate the
functional relevance of the discovered genomic markers. This approach will allow
more rigour and reproducible research in the field of exercise genomics
aerobic-related and resistance-related phenotypes. In total we highlight 12 SNPs
and 7 SNPs that are robustly associated with variance in aerobic-related and
resistance-related phenotypes respectively. To date, there is very little
literature ascribed to understanding the interplay between genes and
environmental factors and the development of physiological traits. We discuss
future directions, including large-scale exercise studies to elucidate the
functional relevance of the discovered genomic markers. This approach will allow
more rigour and reproducible research in the field of exercise genomics
History
Journal
International journal of sports medicineVolume
42Issue
1Pagination
3 - 18Publisher
Georg Thieme VerlagLocation
Stuttgart, GermanyPublisher DOI
Link to full text
ISSN
0172-4622eISSN
1439-3964Language
EnglishPublication classification
C1 Refereed article in a scholarly journalUsage metrics
Categories
Keywords
aerobic exerciseAPOLIPOPROTEIN-E POLYMORPHISMENDURANCE CAPACITYENZYME INSERTION\/DELETION GENOTYPEexercise geneticsgenetic variantsGENOME-WIDE ASSOCIATIONINTERINDIVIDUAL VARIABILITYLife Sciences & BiomedicineMAXIMAL OXYGEN-UPTAKEMUSCLE STRENGTH RESPONSEPHYSICAL PERFORMANCEPROLIFERATOR-ACTIVATED RECEPTORresistance exerciseScience & TechnologySKELETAL-MUSCLESNPsSport Sciencestrainability