Mathematical approaches in estimating aptamer-target binding affinity

Thevendran, Ramesh; Navien, Tholasi Nadhan; Meng, Xin; Wen, Kechun; Lin, Qiao; Shigdar, Sarah; Tang, Thean-Hock; Citartan, Marimuthu

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Mathematical approaches in estimating aptamer-target binding affinity

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posted on 2020-07-01, 00:00 authored by Ramesh Thevendran, Tholasi Nadhan Navien, Xin Meng, Kechun Wen, Qiao Lin, Sarah ShigdarSarah Shigdar, Thean-Hock Tang, Marimuthu Citartan

Mathematical approaches in estimating aptamer-target binding affinity

History

Journal

Analytical Biochemistry

Volume

600

Article number

113742

Pagination

1 - 13

Publisher

Elsevier BV

Location

Amsterdam, The Netherlands

Publisher DOI

https://doi.org/10.1016/j.ab.2020.113742

ISSN

0003-2697

Language

eng

Publication classification

C1 Refereed article in a scholarly journal

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Keywords

Aptamers-target interactions Binding affinity Mathematical models Mathematical approaches Binding curve KD values K(D) values

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File(s) under permanent embargo

Mathematical approaches in estimating aptamer-target binding affinity

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