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Microbiota-Pain Association; Recent Discoveries and Research Progress

journal contribution
posted on 2023-04-04, 00:05 authored by Naser Alizadeh, Ghazal Naderi, Mohammad KahriziMohammad Kahrizi, Tannaz Haghgouei, Ahmad Mobed, Mehran Ebrahimi shah-abadi
The relationship between gut microbiota and pain, such as visceral pain, headaches (migraine), itching, prosthetic joint infection (PJI), chronic abdominal pain (CAP), joint pain, etc., has received increasing attention. Several parts of the evidence suggest that microbiota is one of the most important pain modulators and they can regulate pain in the central and peripheral nervous systems. Any alteration in microbiota by diet or antibiotics mediation may characterize a novel therapeutic strategy for pain management. The present study includes the most up-to-date and influential scientific findings on the association of microbiota with pain, despite the fact that the underlying mechanism is not identified in most cases. According to recent research, identifying the molecular mechanisms of the microbiota-pain pathway can have a unique perspective in treating many diseases, even though there is a long way to reach the ideal point. This study will stress the influence of microbiota on the common diseases that can stimulate the pain with a focus on underlying mechanisms.

History

Journal

Current Microbiology

Volume

80

Article number

29

Pagination

29-

Location

United States

ISSN

0343-8651

eISSN

1432-0991

Language

en

Issue

1

Publisher

Springer Science and Business Media LLC