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Microstructures, mechanical properties and in vitro corrosion behaviour of biodegradable Mg-Zr-Ca alloys

journal contribution
posted on 2013-02-01, 00:00 authored by Y L Zhou, Yuncang Li, D M Luo, Cui'E Wen, Peter HodgsonPeter Hodgson
The microstructures, mechanical properties, corrosion behaviour and biocompatibility of the Mg-Zr-Ca alloys have been investigated for potential use in orthopaedic applications. The microstructures of the alloys were examined using X-ray diffraction analysis, optical microscopy and scanning electron microscopy. The mechanical properties of Mg-Zr-Ca alloys were determined from compressive tests. The corrosion behaviour has been investigated using an immersion test and electrochemical measurement. The biocompatibility was evaluated by cell growth factor using osteoblast-like SaOS2 cell. The experimental results indicate that the hot-rolled Mg-Zr-Ca alloys exhibit much finer microstructures than the as-cast Mg-Zr-Ca alloys which show coarse microstructures. The compressive strength of the hot-rolled alloys is much higher than that of the as-cast alloys and the human bone, which would offer appropriate mechanical properties for orthopaedic applications. The corrosion resistance of the alloys can be enhanced significantly by hot-rolling process. Hot-rolled Mg-0.5Zr-1Ca alloy (wt %) exhibits the lowest corrosion rate among all alloys studied in this paper. The hot-rolled Mg-0.5Zr-1Ca and Mg-1Zr-1Ca alloys exhibit better biocompatibility than other studied alloys and possess advanced mechanical properties, corrosion resistance and biocompatibility, suggesting that they have a great potential to be good candidates for orthopaedic applications. © 2012 Springer Science+Business Media New York.

History

Journal

Journal of materials science

Volume

48

Issue

4

Pagination

1632 - 1639

Publisher

Springer

Location

Berlin, Germany

ISSN

0022-2461

eISSN

1573-4803

Language

eng

Publication classification

C1 Refereed article in a scholarly journal

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