Deakin University
Browse

Molecular design of inorganic-binding polypeptides

Version 2 2024-06-03, 17:43
Version 1 2017-08-04, 12:01
journal contribution
posted on 2024-06-03, 17:43 authored by JS Evans, R Samudrala, Tiffany WalshTiffany Walsh, EE Oren, C Tamerler
Controlled binding and assembly of peptides onto inorganic substrates is at the core of bionanotechnology and biological-materials engineering. Peptides offer several unique advantages for developing future inorganic materials and systems. First, engineered polypeptides can molecularly recognize inorganic surfaces that are distinguishable by shape, crystallography, mineralogy, and chemistry. Second, polypeptides are capable of self-assembly on specific material surfaces leading to addressable molecular architectures. Finally, genetically engineered peptides offer multiple strategies for their functional modification. In this article, we summarize the details and mechanisms involved in combinatorial-polypeptide sequence selection and inorganic-material recognition and affinity, and outline experimental and theoretical approaches and concepts that will help advance this emerging field.

History

Journal

MRS bulletin

Volume

33

Pagination

514-518

ISSN

0883-7694

Language

eng

Publication classification

CN.1 Other journal article

Issue

5

Publisher

Cambridge University Press

Usage metrics

    Research Publications

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC