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Molecular interconversion behaviour in comprehensive two-dimensional gas chromatography
journal contribution
posted on 2004-04-09, 00:00 authored by P Marriott, K Aryusuk, Robert ShellieRobert Shellie, D Ryan, K Krisnangkura, V Schurig, O TrappComprehensive two-dimensional gas chromatography (GC x GC) is shown to provide information on dynamic molecular behaviour (interconversion), with the interconversion process occurring on both columns in the coupled-column experiment. The experiment requires suitable adjustment of both experimental conditions and relative dimensions of each of the columns. In this case, a longer column than normally employed in GC x GC allows sufficient retention duration on the second column, which permits the typical plateau-shape recognised for the interconversion process to be observed. The extent of interconversion depends on prevailing temperature, retention time, and the phase type. Polyethylene glycol-based phases were found to result in high interconversion kinetics, although terephthalic acid-terminated polyethylene glycol had a lesser extent of interconversion. Much less interconversion was seen for phenyl-methylpolysiloxane and cyclodextrin phases. This suggests that for the oximes, interconversion largely occurs in the stationary phase. Examples of different extents of interconversion in both dimensions are shown, including peak coalescence on the first column with little interconversion on the second column.
History
Journal
Journal of chromatography AVolume
1033Issue
1Pagination
135 - 143Publisher
ElsevierLocation
Amsterdam, The NetherlandsPublisher DOI
ISSN
0021-9673Language
engPublication classification
C1.1 Refereed article in a scholarly journalCopyright notice
2004, Elsevier B.V.Usage metrics
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Molecular interconversionDynamic gas chromatographyGas chromatography, comprehensive two-dimensionalAcetaldoximeButyraldoximeOximesScience & TechnologyLife Sciences & BiomedicinePhysical SciencesBiochemical Research MethodsChemistry, AnalyticalBiochemistry & Molecular BiologyChemistrygas chromatographycomprehensive two-dimensionalENANTIOMERIZATION BARRIERSDYNAMIC CHROMATOGRAPHYENERGY BARRIERSEPARATIONBIPHENYLSPROFILESSIMULATIONREACTOR
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