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Molecular recognition of physiological substrate noradrenaline by the adrenaline-synthesizing enzyme PNMT and factors influencing its methyltransferase activity.
journal contribution
posted on 2009-09-01, 00:00 authored by N Drinkwater, C Gee, Munish Puri, K Criscione, M McLeish, G Grunewald, J MartinMolecular recognition of physiological substrate noradrenaline by the adrenaline-synthesizing enzyme PNMT and factors influencing its methyltransferase activity.
History
Journal
Biochemical journalVolume
422Issue
3Pagination
463 - 471Publisher
Portland PressLocation
London, EnglandPublisher DOI
ISSN
0264-6021eISSN
1470-8728Language
engPublication classification
C1 Refereed article in a scholarly journal; C Journal articleCopyright notice
2009, Portland PressUsage metrics
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No categories selectedKeywords
Science & TechnologyLife Sciences & BiomedicineBiochemistry & Molecular Biologycatecholamine synthesisenzyme catalysisnoradrenochromevariant phenylethanolamine N-methyltransferase (PNMT)substrate specificityPHENYLETHANOLAMINE N-METHYLTRANSFERASECRYSTAL-STRUCTUREINHIBITORSBINDINGSITEBRAINAMINOSULFONYL)-1,2,3,4-TETRAHYDROISOQUINOLINESCRYSTALLOGRAPHYSOFTWARESYSTEMS
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