File(s) not publicly available
Musculoskeletal Deficits and Cognitive Impairment: Epidemiological Evidence and Biological Mechanisms
journal contribution
posted on 2023-02-09, 05:01 authored by Sophia Sui, J Balanta-Melo, Julie PascoJulie Pasco, L I PlotkinPurpose of Review: Cognitive impairment is associated with obesity, sarcopenia, and osteoporosis. However, no critical appraisal of the literature on the relationship between musculoskeletal deficits and cognitive impairment, focusing on the epidemiological evidence and biological mechanisms, has been published to date. Herein, we critically evaluate the literature published over the past 3 years, emphasizing interesting and important new findings, and provide an outline of future directions that will improve our understanding of the connections between the brain and the musculoskeletal system. Recent Findings: Recent literature suggests that musculoskeletal deficits and cognitive impairment share pathophysiological pathways and risk factors. Cytokines and hormones affect both the brain and the musculoskeletal system; yet, lack of unified definitions and standards makes it difficult to compare studies. Summary: Interventions designed to improve musculoskeletal health are plausible means of preventing or slowing cognitive impairment. We highlight several musculoskeletal health interventions that show potential in this regard.
History
Journal
Current Osteoporosis ReportsPublisher DOI
ISSN
1544-1873eISSN
1544-2241Usage metrics
Categories
No categories selectedKeywords
Licence
Exports
RefWorks
BibTeX
Ref. manager
Endnote
DataCite
NLM
DC