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Nano-lactoferrin in diagnostic, imaging and targeted delivery for cancer and infectious diseases

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journal contribution
posted on 2012-03-07, 00:00 authored by Jagat Kanwar, Rasika Samarasinghe, R Sehgal, Rupinder Kanwar
Lactoferrin (Lf) is a natural occurring iron binding protein present in many mammalian excretions and involved in various physiological processes. Lf is used in the transport of iron along with other molecules and ions from the digestive system. However its the modulatory functions exhibited by Lf in connection to immune response, disease regression and diagnosis that has made this protein an attractive therapeutic against chronic diseases. Further, the exciting potentials of employing nanotechnology in advancing drug delivery systems, active disease targeting and prognosis have also shown some encouraging outcomes. This review focuses on the role of Lf in diagnosing infection, cancer, neurological and inflammatory diseases and the recent nanotechnology based strategies.

History

Journal

Journal of cancer science & therapy

Volume

4

Issue

3

Pagination

31 - 42

Publisher

OMICS Group

Location

Westlake, Calif.

ISSN

1948-5956

Language

eng

Publication classification

C1.1 Refereed article in a scholarly journal

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