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Nanogels for skin cancer therapy via transdermal delivery: current designs
journal contribution
posted on 2019-01-01, 00:00 authored by Phuong TranPhuong Tran, Wei DuanWei Duan, B J Lee, T T D Tran© 2019 Bentham Science Publishers. Background: Recently, several strategies have been proposed for skin cancer therapy by transdermal delivery, and particularly the use of nanotechnology. Methods: This process disrupts the stratum corneum to deliver a drug through the skin, allowing it to accumulate at the tumor site. Results: Nanogels are drug delivery systems that can be applied to many diseases. Nanogel engineering has been widely studied for use in drug delivery, particularly in cancer theranostics. This review summarizes specific strategies for using nanogels to treat skin cancer, a topic that is limited in recent literature. Conclusion: Advanced techniques for effective skin cancer therapy based on the nanogel’s penetration and cellular uptake abilities will be discussed. Moreover, techniques for penetrating the skin, as well as drug release, permeation studies, and microscopic observations, will also be discussed.
History
Journal
Current drug metabolismVolume
20Issue
7Pagination
575 - 582Publisher
Bentham Science PublishersLocation
Beijing, ChinaPublisher DOI
ISSN
1389-2002eISSN
1875-5453Language
engPublication classification
C1 Refereed article in a scholarly journalCopyright notice
2019, Bentham Science PublishersUsage metrics
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No categories selectedKeywords
Science & TechnologyLife Sciences & BiomedicineBiochemistry & Molecular BiologyPharmacology & PharmacyNanotechnologyskin cancernanogelspenetrationtransdermal drug deliverycellular uptakeINFRARED FLUORESCENCE PROBEIRON-OXIDE NANOPARTICLESCONTROLLED DRUG-DELIVERYLOADED CHITIN NANOGELSOLEIC ACID CONJUGATEIN-VITROLIPID NANOPARTICLESTUMOR MICROENVIRONMENTTHERANOSTIC NANOPARTICLEStransdermal drug delivery.
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