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Neurobehavioral consequences of prenatal antiepileptic drug exposure
journal contribution
posted on 2012-01-01, 00:00 authored by C Nadebaum, V Anderson, F Vajda, D Reutens, Amanda WoodAmanda WoodDespite elevated rates of birth defects associated with prenatal antiepileptic drug exposure, pharmacotherapy is typically continued throughout pregnancy because of the risks posed to mother and child by recurrent seizures. Emerging data suggest that prenatal exposure to valproate or polytherapy may also be associated with increased risk of cognitive impairment. However, our understanding of the longer-term sequelae of prenatal antiepileptic drug exposure remains incomplete. Improved understanding of the neurobehavioral consequences of prenatal antiepileptic drug exposure is essential to ensure accurate information is available for women with epilepsy planning a pregnancy, and to achieve optimal outcomes for mothers and children.
History
Journal
Developmental neuropsychologyVolume
37Issue
1Pagination
1 - 29Publisher
Taylor & FrancisLocation
Abingdon, Eng.Publisher DOI
ISSN
8756-5641Language
engPublication classification
C1.1 Refereed article in a scholarly journalUsage metrics
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Categories
Keywords
prenatal antiepileptic drug exposurebirth defectspharmacotherapySocial SciencesPsychology, DevelopmentalPsychologyPsychology, ExperimentalFETAL VALPROATE SYNDROMEIN-UTERO EXPOSUREAUTISM SPECTRUM DISORDERSPSYCHOMOTOR DEVELOPMENTCHILDREN BORNPSYCHOLOGICAL-DEVELOPMENTANTICONVULSANT SYNDROMEPREGNANCY REGISTRIESEPILEPTIC PARENTSMATERNAL EPILEPSY