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No evidence that spice consumption is a cancer prevention mechanism in human populations
journal contribution
posted on 2023-03-31, 00:41 authored by Antoine DujonAntoine Dujon, Aurélie Tasiemski, Pascal Pujol, Anthony Turpin, Beata UjvariBeata Ujvari, Frédéric ThomasAbstract
Why humans historically began to incorporate spices into their diets is still a matter of unresolved debate. For example, a recent study (Bromham et al. 2021, Nat Hum Behav) did not support the most popular hypothesis that spice consumption was a practice favoured by selection in certain environments to reduce food poisoning, parasitic infections, and foodborne diseases. Because several spices are known to have anticancer effects, we explored, using the same dataset, the hypothesis that natural selection and/or cultural evolution may have favoured spice consumption as an adaptive prophylactic response to reduce the burden of cancerous pathologies. Patterns of spice use in 36 countries, however, are not consistent with a cancer mitigation mechanism: the age-standardised rate of almost all gastrointestinal cancers was not related to spice consumption. Thus, directions other than foodborne pathogens and cancers should be explored to understand the health reasons, if any, why our ancestors developed a taste for spices.
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Journal
Evolution, Medicine, and Public HealthVolume
11Pagination
45-52Location
Oxford, Eng.Publisher DOI
ISSN
2050-6201eISSN
2050-6201Language
enPublication classification
C1 Refereed article in a scholarly journalIssue
1Publisher
Oxford University Press (OUP)Usage metrics
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