marx-nutraceuticalsas-2021.pdf (11.13 MB)
Nutraceuticals as potential targets for the development of a functional beverage for improving sleep quality
journal contribution
posted on 2021-06-03, 00:00 authored by A Bulman, N M D’cunha, Wolf MarxWolf Marx, A J McKune, R Jani, N NaumovskiFunctional beverages can be a valuable component of the human diet with the ability to not only provide essential hydration but to deliver important bioactive compounds that can contribute to chronic disease treatment and prevention. One area of the functional beverage market that has seen an increase in demand in recent years are beverages that promote relaxation and sleep. Sleep is an essential biological process, with optimal sleep being defined as one of adequate duration, quality and timing. It is regulated by a number of neurotransmitters which are, in turn, regulated by dietary intake of essential bioactive compounds. This narrative review aimed to evaluate the latest evidence of the sleep promoting properties of a selection of bioactive compounds (such as L-theanine and L-tryptophan) for the development of a functional beverage to improve sleep quality; and the effectiveness of traditional sleep promoting beverages (such as milk and chamomile). Overall, the bioactive compounds identified in this review, play essential roles in the synthesis and regulation of important neurotransmitters involved in the sleep-wake cycle. There is also significant potential for their inclusion in a number of functional beverages as the main ingredient on their own or in combination. Future studies should consider dosage; interactions with the beverage matrix, medications and other nutraceuticals; bioavailability during storage and following ingestion; as well as the sensory profile of the developed beverages, among others, when determining their effectiveness in a functional beverage to improve sleep quality.
History
Journal
BeveragesVolume
7Issue
2Article number
ARTN 33Pagination
1 - 30Publisher
MDPI / MDPI AG (Multidisciplinary Digital Publishing Institute)Location
Basel, SwitzerlandPublisher DOI
Link to full text
ISSN
2306-5710eISSN
2306-5710Language
EnglishPublication classification
C1 Refereed article in a scholarly journalUsage metrics
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BIOACTIVE COMPOUNDSchamomile extractcysteineDOUBLE-BLINDFood Science & Technologyfunctional beveragesGENERALIZED ANXIETY DISORDERGREEN TEAKYNURENINE PATHWAYLife Sciences & BiomedicineL-THEANINEnutraceuticalsPRIMARY INSOMNIAScience & TechnologysleeptheaninetryptophanTRYPTOPHAN-METABOLISMVITAMIN-D LEVELSZINC SUPPLEMENTATION
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