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Nutritional status of children with cystic fibrosis measured by total body potassium as a marker of body cell mass: lack of sensitivity of anthropometric measures
journal contribution
posted on 2000-02-01, 00:00 authored by Sarah McNaughtonSarah McNaughton, R W Shepherd, R G Greer, G J Cleghorn, B J ThomasOBJECTIVE: To investigate measures aimed at defining the nutritional status of cystic fibrosis (CF) populations, this study compared standard anthropometric measurements and total body potassium (TBK) as indicators of malnutrition. METHODS: Height, weight, and TBK measurements of 226 children with CF from Royal Children's Hospital, Brisbane, Australia, were analyzed. Z scores for height for age, weight for age, and weight for height were analyzed by means of the National Centre for Health Statistics reference. TBK was measured by means of whole body counting and compared with predicted TBK for age. Two criteria were evaluated with respect to malnutrition: (1) a z score < -2.0 and (2) a TBK for age <80% of predicted. RESULTS: Males and females with CF had lower mean height-for-age and weight-for-age z scores than the National Centre for Health Statistics reference (P <.01), but mean weight-for-height z score was not significantly different. There were no significant gender differences. According to anthropometry, only 7.5% of this population were underweight and 7.6% were stunted. However, with TBK as an indicator of nutritional status, 29.9% of males and 22.0% of females were malnourished. CONCLUSION: There are large differences in the percentage of patients with CF identified as malnourished depending on whether anthropometry or body composition data are used as the nutritional indicator. At an individual level, weight-based indicators are not sensitive indicators of suboptimal nutritional status in CF, significantly underestimating the extent of malnutrition. Current recommendations in which anthropometry is used as the indicator of malnutrition in CF should be revised.
History
Journal
Journal of pediatricsVolume
136Issue
2Pagination
188 - 194Publisher
ElsevierLocation
Amsterdam, The NetherlandsPublisher DOI
ISSN
0022-3476Language
engPublication classification
C1.1 Refereed article in a scholarly journalCopyright notice
2000, Mosby, Inc.Usage metrics
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No categories selectedKeywords
Body CompositionBody HeightBody WeightChildCross-Sectional StudiesCystic FibrosisFemaleHumansMaleNutrition DisordersNutritional StatusPotassiumSensitivity and SpecificityScience & TechnologyLife Sciences & BiomedicinePediatricsBIOELECTRICAL IMPEDANCE ANALYSISMUSCLE PROTEIN-DEGRADATIONGROWTH-RETARDED CHILDRENLEUCINE METABOLISMENERGY-EXPENDITUREANOREXIA-NERVOSAREHABILITATIONMALNUTRITIONADOLESCENTSDISEASE
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