sui-obesityandbrain-2020.pdf (256.98 kB)
Obesity and brain function: The brain–body crosstalk
Dementia comprises a wide range of progressive and acquired neurocognitive disorders. Obesity, defined as excessive body fat tissue, is a common health issue world-wide and a risk factor for dementia. The adverse effects of obesity on the brain and the central nervous system have been the subject of considerable research. The aim of this review is to explore the available evidence in the field of body–brain crosstalk focusing on obesity and brain function, to identify the major research measurements and methodologies used in the field, to discuss the potential risk factors and biological mechanisms, and to identify the research gap as a precursor to systematic reviews and empirical studies in more focused topics related to the obesity–brain relationship. To conclude, obesity appears to be associated with reduced brain function. However, obesity is a complex health condition, while the human brain is the most complicated organ, so research in this area is difficult. Inconsistency in definitions and measurement techniques detract from the literature on brain–body relationships. Advanced techniques developed in recent years are capable of improving investigations of this relationship.
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MedicinaVolume
56Issue
10 - Special Issue: Exercise Physiology, Muscle Function and RehabilitationArticle number
499Publisher
MDPI AGLocation
Basel, SwitzerlandPublisher DOI
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1010-660XeISSN
1010-660XLanguage
engNotes
This article belongs to the Special Issue: Exercise Physiology, Muscle Function and RehabilitationPublication classification
C1 Refereed article in a scholarly journalCopyright notice
2020, The AuthorsUsage metrics
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