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Obesity is associated with previous suicide attempts in bipolar disorder

Version 2 2024-05-30, 15:29
Version 1 2014-10-28, 09:14
journal contribution
posted on 2024-05-30, 15:29 authored by FA Gomes, M Kauer-Sant'Anna, PV Magalhães, Felice JackaFelice Jacka, Seetal DoddSeetal Dodd, CS Gama, A Cunha, Michael BerkMichael Berk, F Kapczinski
Gomes FA, Kauer-Sant’Anna M, Magalhães PV, Jacka FN, Dodd S, Gama CS, Cunha Â, Berk M, Kapczinski F. Obesity is associated with previous suicide attempts in bipolar disorder.Objective:There is a paucity of data about risk factors for suicide attempts in bipolar disorder. The aim of this study is to examine the association between suicide attempts and obesity in people with bipolar disorder.Methods:Two hundred fifty-five DSM-IV out-patients with bipolar disorder were consecutively recruited from the Bipolar Disorder Program at Hospital das Clínicas de Porto Alegre and the University Hospital at the Universidade Federal de Santa Maria, Brazil. Diagnosis and clinical variables were assessed with Structured Clinical Interview for DSM-IV-axis I (SCID I) and Program structured protocol. History of suicide attempts was obtained from multiple information sources including patients, relatives and review of medical records. Patients with body mass index (BMI) ≥ 30 were classified as obese.Results:Over 30% of the sample was obese and over 50% had a history of suicide attempt. In the multivariate model, obese patients were nearly twice (OR = 1.97, 95% CI: 1.06–3.69, p = 0.03) as likely to have a history of suicide attempt(s).Conclusion:Our results emphasise the relevance of obesity as an associated factor of suicide attempts in bipolar disorder. Obesity may be seen as correlate of severity and as such, must be considered in the comprehensive management of bipolar patients.

History

Journal

Acta Neuropsychiatrica

Volume

22

Pagination

63-67

Location

England

ISSN

0924-2708

eISSN

1601-5215

Language

English

Publication classification

C1.1 Refereed article in a scholarly journal

Copyright notice

2010, John Wiley & Sons

Issue

2

Publisher

CAMBRIDGE UNIV PRESS