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Osteoporosis and the critically ill patient
journal contribution
posted on 2019-04-01, 00:00 authored by Neil OrfordNeil Orford, Julie PascoJulie Pasco, Mark KotowiczMark KotowiczImproved survival after critical illness has led to recognition of impaired recovery following critical illness as a major public health problem. A consistent association between critical illness and accelerated bone loss has been described, including changes in bone turnover markers, bone mineral density, and fragility fracture rate. An association between accelerated bone turnover and increased mortality after critical illness is probable. Assessment of the effect of antifracture agents on fracture rate and mortality in the high-risk population of postmenopausal women with prolonged ventilation is warranted.
History
Journal
Critical care clinicsVolume
35Issue
2Pagination
301 - 313Publisher
ElsevierLocation
Amsterdam, The NetherlandsPublisher DOI
eISSN
1557-8232Language
engPublication classification
C1 Refereed article in a scholarly journalCopyright notice
2018, Elsevier Inc.Usage metrics
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No categories selectedKeywords
Bone lossBone mineral densityCritical illnessFractureLong-term outcomesOsteoporosisScience & TechnologyLife Sciences & BiomedicineCritical Care MedicineGeneral & Internal MedicineBONE TURNOVER MARKERSPROLONGED CRITICAL ILLNESSMINERAL DENSITYFRACTURE RISKMORTALITYASSOCIATIONMENHORMONEHYPERRESORPTIONRESORPTION
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