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Overexpression of sphingosine kinase 1 prevents ceramide accumulation and ameliorates muscle insulin resistance in high-fat diet-fed mice

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posted on 2012-12-01, 00:00 authored by Clinton BruceClinton Bruce, S Risis, J Babb, C Yang, Greg KowalskiGreg Kowalski, Ahrathy SelathuraiAhrathy Selathurai, R Lee-Young, J Weir, K Yoshioka, Y Takuwa, P Meikle, S Pitson, M Febbraio
Overexpression of sphingosine kinase 1 prevents ceramide accumulation and ameliorates muscle insulin resistance in high-fat diet-fed mice

History

Journal

Diabetes

Volume

61

Issue

12

Pagination

3148 - 3155

Publisher

American Diabetes Association

Location

Alexandria, Virginia

Publisher DOI

Link to full text

ISSN

0012-1797

eISSN

1939-327X

Language

eng

Publication classification

C1.1 Refereed article in a scholarly journal

Copyright notice

2012, American Diabetes Association

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    Keywords

    sphingosine-1-phosphate (S1P)ceramidebioactive lipidsskeletal muscleinsulin resistanceScience & TechnologyLife Sciences & BiomedicineEndocrinology & MetabolismACTIVATED PROTEIN-KINASEIN-VIVOLIPID-METABOLISMACID OXIDATIONSPHINGOSINE-1-PHOSPHATECELLSINFLAMMATIONADIPONECTINAPOPTOSISPATHWAY

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    All Rights Reserved

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